Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25082363 | 0.87 | SMN1; SMN2 (0.66) | SMN1; SMN2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL538291 | 0.86 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL27659536 | 0.86 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL29860485 | 0.86 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL9607221 | 0.85 | KDM4E (0.56) | SMN1; SMN2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL31440795 | 0.85 | KDM4E (0.56) | SMN1; SMN2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL14238204 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL11075264 | 0.83 | KDM4E (0.61) | SMN1; SMN2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL27327783 | 0.83 | KDM4E (0.57) | SMN1; SMN2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL27276256 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432073-B | A kind of preparation method of the bromo- 4- chloroquinoline of 6- | 上海再启生物技术有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-106432073-A | 6-bromo-4-chloroquinoline preparation method | 上海再启生物技术有限公司 | 2017-02-22 | — | — | CN | disclosed |