Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | NMT2 | O60551 | 1/20 | 0.58 |
| ▸ | NMT1 | P30419 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL538291 | 0.86 | SMN1; SMN2 (0.69) | KDM4EALDH1A1SMN1; SMN2NMT2NMT1 | |
| SCHEMBL29860485 | 0.86 | SMN1; SMN2 (0.58) | KDM4EALDH1A1SMN1; SMN2NMT2NMT1 | |
| SCHEMBL27659536 | 0.86 | SMN1; SMN2 (0.58) | KDM4EALDH1A1SMN1; SMN2NMT2NMT1 | |
| SCHEMBL19002791 | 0.84 | ALDH1A1 (0.66) | KDM4EALDH1A1SMN1; SMN2NMT2NMT1 | |
| SCHEMBL4992903 | 0.84 | FABP3 (0.52) | KDM4EALDH1A1SMN1; SMN2NMT2NMT1 | |
| SCHEMBL395812 | 0.84 | SMN1; SMN2 (0.53) | KDM4EALDH1A1SMN1; SMN2NMT2NMT1 | |
| SCHEMBL28126276 | 0.83 | SMN1; SMN2 (0.55) | KDM4EALDH1A1SMN1; SMN2NMT2NMT1 | |
| SCHEMBL14238204 | 0.83 | SMN1; SMN2 (0.55) | KDM4EALDH1A1SMN1; SMN2NMT2NMT1 | |
| SCHEMBL27276256 | 0.83 | SMN1; SMN2 (0.55) | KDM4EALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL27327783 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2NMT2NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450167-A | TRANQUILIZERS; PSYCHOLOGICAL DISORDERS | ROUSSEL UCLAF (FR) | 1984-05-22 | — | — | US | disclosed |