Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HCAR3 | P49019 | 10/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28644813 | 0.84 | KMT2A (0.58) | KMT2AHCAR3HTTMAPTNPSR1 | |
| SCHEMBL6506088 | 0.83 | KMT2A (0.62) | KMT2AHCAR3HTTMAPTNPSR1 | |
| SCHEMBL3616520 | 0.81 | KMT2A (0.70) | KMT2AHCAR3HTTLMNASMN1; SMN2 | |
| SCHEMBL28388705 | 0.80 | KMT2A (0.64) | KMT2AHCAR3HTTLMNASMN1; SMN2 | |
| SCHEMBL571622 | 0.80 | KMT2A (0.64) | KMT2AHCAR3HTTLMNASMN1; SMN2 | |
| SCHEMBL3613079 | 0.79 | HCAR3 (0.72) | KMT2AHCAR3MAPTNPSR1MEN1 | |
| SCHEMBL9197268 | 0.78 | KMT2A (0.62) | KMT2AHCAR3HTTLMNAMAPT | |
| SCHEMBL2643864 | 0.78 | KMT2A (0.68) | KMT2AHCAR3HTTMAPTNPSR1 | |
| SCHEMBL29793669 | 0.78 | KMT2A (0.68) | KMT2AHCAR3HTTMAPTNPSR1 | |
| SCHEMBL3614454 | 0.76 | KMT2A (0.60) | KMT2AHCAR3HTTMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106518850-A | Chemical synthesis method of Pimobendan | 青岛农业大学 | 2017-03-22 | — | — | CN | disclosed |