SCHEMBL28126451

SCHEMBL28126451

CC(C)(C)O[C]=O.O=COCC1c2ccccc2-c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
HTR2A P28223 1/20 0.34
KMT2A Q03164 2/20 0.34
FABP5 Q01469 3/20 0.33
FABP7 O15540 2/20 0.33
EPHX2 P34913 1/20 0.32
CASP3 P42574 1/20 0.32
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29393453 0.83 CA1 (0.53) CA1CA2HTR2AKMT2AFABP5
SCHEMBL12719 0.83 CA1 (0.53) CA1CA2HTR2AKMT2AFABP5
SCHEMBL28202099 0.82 CA1 (0.44) CA1CA2HTR2AKMT2AFABP5
SCHEMBL28101345 0.82 CA1 (0.44) CA1CA2HTR2AKMT2AFABP5
SCHEMBL27768296 0.82 CA1 (0.41) CA1CA2HTR2AKMT2AFABP5
Tert-Butyl Formate SCHEMBL2890845 0.79 CA1 (0.41) CA1CA2HTR2AKMT2AFABP5
Methylene Chloride SCHEMBL28181606 0.79 CA1 (0.49) CA1CA2HTR2AKMT2AFABP5
Dimethylformamide SCHEMBL28264885 0.78 CA1 (0.45) CA1CA2HTR2AKMT2AFABP5
Diethylamine SCHEMBL28081949 0.78 CA1 (0.45) CA1CA2HTR2AKMT2AFABP5
SCHEMBL21843101 0.74 CA1 (0.42) CA1CA2HTR2AKMT2AFABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103387601-B Anti-dengue virus (DENV) heterocyclic peptide compounds and preparing methods and uses thereof 南开大学 2017-01-11 CN disclosed