SCHEMBL27768296

SCHEMBL27768296

CC(C)(C)O[C]=O.C[C]=O.O=[C]OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
HTR2A P28223 1/20 0.35
KMT2A Q03164 2/20 0.35
FABP5 Q01469 3/20 0.34
FABP7 O15540 2/20 0.34
EPHX2 P34913 1/20 0.33
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7764 0.84 CA1 (0.53) CA1CA2HTR2AKMT2AFABP5
Tert-Butyl Formate SCHEMBL2890845 0.83 CA1 (0.41) CA1CA2HTR2AKMT2AFABP5
SCHEMBL28126451 0.82 CA1 (0.40) CA1CA2HTR2AKMT2AFABP5
Dimethylformamide SCHEMBL28310394 0.77 CA1 (0.43) CA1CA2HTR2AKMT2AFABP5
SCHEMBL28101345 0.75 CA1 (0.44) CA1CA2HTR2AKMT2AFABP5
SCHEMBL28310443 0.75 CA1 (0.44) CA1CA2HTR2AKMT2AFABP5
SCHEMBL28152768 0.74 KMT2A (0.39) KMT2AFABP5FABP7EPHX2
SCHEMBL22320252 0.73 HTR2A (0.40) CA1CA2HTR2AFABP5
Hydrochloric Acid SCHEMBL28129901 0.73 KMT2A (0.38) CA1CA2KMT2AFABP5FABP7
SCHEMBL18055683 0.72 CA1 (0.42) CA1CA2HTR2AKMT2AFABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101466392-A Pharmaceutical composition for preventing or treating HIV infection and application thereof TIANJIN FUSOGEN PHARMACEUTICAL (CN) 2009-06-24 CN disclosed