SCHEMBL28126602

SCHEMBL28126602

CCOc1c(C(=O)OC)ccc(C(=O)OC)c1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.48
KMT2A Q03164 1/20 0.42
PTGER4 P35408 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
PDK2 Q15119 1/20 0.41
PDK4 Q16654 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
TSHR P16473 2/20 0.40
ALDH1A1 P00352 6/20 0.40
HTT P42858 1/20 0.40
KDM4E B2RXH2 6/20 0.39
MAPT P10636 4/20 0.39
HSD17B10 Q99714 3/20 0.39
HPGD P15428 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HCRTR1 O43613 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28126645 0.87 TSHR (0.55) KMT2ACA12CA1CA2CA7
SCHEMBL17559391 0.87 KMT2A (0.44) TDP1KMT2APTGER4CA12CA1
SCHEMBL12075084 0.81 TSHR (0.50) TDP1KMT2ACA12CA1CA2
SCHEMBL27904110 0.81 TDP1 (0.54) TDP1KMT2ATSHRALDH1A1HTT
SCHEMBL19602445 0.80 TDP1 (0.43) TDP1KMT2ACA12CA1CA2
SCHEMBL17559334 0.80 PRMT5 (0.55) TSHRALDH1A1KDM4EMAPTHSD17B10
SCHEMBL16959103 0.79 TSHR (0.46) TDP1KMT2ATSHRALDH1A1KDM4E
SCHEMBL28126893 0.79 TSHR (0.46) TDP1CA12CA1CA2CA7
SCHEMBL15726037 0.79 LMNA (0.58) TDP1KMT2ATSHRALDH1A1KDM4E
SCHEMBL31634962 0.78 TDP1 (0.48) TDP1KMT2ATSHRALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106543314-B The application of catalyst containing ether ester and the catalyst and ether ester in olefin polymerization 中国石油化工股份有限公司 2019-02-19 CN claimed
CN-106543312-A A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2017-03-29 CN claimed
CN-106543314-A The application of catalyst containing ether ester and the catalyst and ether ester in olefinic polyreaction 中国石油化工股份有限公司 2017-03-29 CN claimed
CN-106543313-A A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2017-03-29 CN claimed
CN-106543310-A A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2017-03-29 CN claimed
CN-106543310-B A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2019-06-28 CN disclosed
CN-106543312-B A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2019-06-28 CN disclosed
CN-106543313-B A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2019-06-28 CN disclosed
CN-106543314-B The application of catalyst containing ether ester and the catalyst and ether ester in olefin polymerization 中国石油化工股份有限公司 2019-02-19 CN disclosed
CN-106543312-A A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2017-03-29 CN disclosed
CN-106543314-A The application of catalyst containing ether ester and the catalyst and ether ester in olefinic polyreaction 中国石油化工股份有限公司 2017-03-29 CN disclosed
CN-106543313-A A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2017-03-29 CN disclosed
CN-106543310-A A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2017-03-29 CN disclosed