Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2812681 | 1.00 | ADORA2A (0.80) | ADORA2ACYP3A4ADORA1KCNH2 | |
| SCHEMBL2809428 | 0.82 | ADORA2A (0.78) | ADORA2ACYP3A4ADORA1KCNH2 | |
| SCHEMBL2809424 | 0.82 | ADORA2A (0.78) | ADORA2ACYP3A4ADORA1KCNH2 | |
| SCHEMBL13171850 | 0.82 | ADORA2A (0.80) | ADORA2ACYP3A4ADORA1KCNH2 | |
| SCHEMBL2811393 | 0.81 | ADORA2A (0.75) | ADORA2ACYP3A4ADORA1KCNH2 | |
| SCHEMBL2811398 | 0.81 | ADORA2A (0.75) | ADORA2ACYP3A4ADORA1KCNH2 | |
| SCHEMBL2810792 | 0.80 | ADORA2A (0.65) | ADORA2ACYP3A4ADORA1KCNH2 | |
| SCHEMBL2810257 | 0.73 | ADORA2A (1.00) | ADORA2ACYP3A4ADORA1KCNH2 | |
| SCHEMBL2815231 | 0.70 | ADORA2A (1.00) | ADORA2ACYP3A4ADORA1 | |
| SCHEMBL2812075 | 0.70 | ADORA2A (1.00) | ADORA2ACYP3A4ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249084-A1 | SUBSTITUTED PYRIMIDINES AS ADENOSINE RECEPTOR ANTAGONISTS | ALMIRALL, S.A. (ES) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249084-A1 | SUBSTITUTED PYRIMIDINES AS ADENOSINE RECEPTOR ANTAGONISTS | ADORA3, ADORA1, ADORA2A | ADORA2A 3/4885CYP3A4 965/4885ADORA1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.