Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.64 |
| ▸ | MIF | P14174 | 1/20 | 0.60 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.60 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | GLA | P06280 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | CASP1 | P29466 | 3/20 | 0.57 |
| ▸ | CASP7 | P55210 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13231988 | 0.83 | MCL1 (0.55) | AKR1B1MIFPFKFB3ALDH1A1KDM4E | |
| SCHEMBL15842563 | 0.83 | KDM4E (0.59) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL741818 | 0.80 | CA12 (0.56) | AKR1B1MIFPFKFB3ALDH1A1KDM4E | |
| SCHEMBL13232055 | 0.80 | HSD17B3 (0.61) | AKR1B1HSD17B3ALDH1A1KDM4EGAA | |
| SCHEMBL3055094 | 0.79 | HSD17B3 (0.63) | AKR1B1MIFHSD17B3ALDH1A1KDM4E | |
| SCHEMBL11329370 | 0.78 | KDM4E (0.43) | AKR1B1MIFPFKFB3ALDH1A1KDM4E | |
| SCHEMBL3085227 | 0.78 | MCL1 (0.59) | AKR1B1MIFPFKFB3ALDH1A1KDM4E | |
| SCHEMBL4209634 | 0.78 | KDM4E (0.76) | AKR1B1HSD17B3ALDH1A1KDM4EGAA | |
| SCHEMBL11502202 | 0.78 | KDM4E (0.67) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL29495537 | 0.78 | AKR1B1 (1.00) | AKR1B1MIFPFKFB3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149656-B | Curable thermosetting resin and application thereof in high-voltage insulator for switch cabinet | 浙江省开化七一电力器材有限责任公司 | 2023-06-09 | — | — | CN | claimed |
| CN-114149656-A | Curable thermosetting resin and application thereof in high-voltage insulator for switch cabinet | 浙江省开化七一电力器材有限责任公司 | 2022-03-08 | — | — | CN | claimed |
| CN-117590694-A | Photosensitive resin composition, photosensitive resist laminate and application thereof | 杭州福斯特电子材料有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-114149656-B | Curable thermosetting resin and application thereof in high-voltage insulator for switch cabinet | 浙江省开化七一电力器材有限责任公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-114149656-B | Curable thermosetting resin and application thereof in high-voltage insulator for switch cabinet | 浙江省开化七一电力器材有限责任公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-114149656-A | Curable thermosetting resin and application thereof in high-voltage insulator for switch cabinet | 浙江省开化七一电力器材有限责任公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-114149656-A | Curable thermosetting resin and application thereof in high-voltage insulator for switch cabinet | 浙江省开化七一电力器材有限责任公司 | 2022-03-08 | — | — | CN | disclosed |
| US-20100249179-A1 | Farnesoid X Receptor Agonists | SMITHKLINE BEECHAM CORPORATION (US) | 2010-09-30 | — | — | US | disclosed |
| EP-2170072-A1 | FARNESOID X RECEPTOR AGONISTS | GlaxoSmithKline LLC (US) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008157270-A1 | FARNESOID X RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |
| WO-2007115181-A9 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEM CO (US) | 2008-04-03 | — | — | WO | disclosed |
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | EASTMAN CHEMICAL COMPANY | 2007-11-01 | — | — | US | disclosed |
| WO-2007115181-A2 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEMICAL COMPANY (US) | 2007-10-11 | — | — | WO | disclosed |
| US-4151291-A | ANALGESICS | UNICLER (FR) | 1979-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | ABCC4, NCOA4, NR4A3 | AKR1B1 384/4885MIF 1992/4885PFKFB3 1541/4885 |
| US-20100249179-A1 | Farnesoid X Receptor Agonists | NR1H4, NR1H3, NR1H2 | AKR1B1 507/4885MIF 2738/4885PFKFB3 2649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.