Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13231988 | 0.89 | MCL1 (0.55) | MCL1NPC1MEN1KMT2AKDM4E | |
| SCHEMBL13232070 | 0.83 | DPP4 (0.49) | MCL1NPC1MEN1KMT2AERAP1 | |
| SCHEMBL13180170 | 0.80 | MCL1 (0.57) | MCL1MEN1KMT2AERAP1TDP1 | |
| SCHEMBL3640665 | 0.78 | MAPT (0.53) | MCL1NPC1MEN1KMT2AKDM4E | |
| SCHEMBL2812687 | 0.78 | AKR1B1 (0.64) | MCL1MEN1KMT2AERAP1KDM4E | |
| SCHEMBL1406180 | 0.76 | MAOB (0.64) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16985170 | 0.76 | MCL1 (0.49) | MCL1MEN1KMT2AERAP1TDP1 | |
| SCHEMBL28047037 | 0.76 | MAOB (0.49) | KMT2AKDM4EBAZ2BBAZ2AMIF | |
| SCHEMBL31357189 | 0.75 | MCL1 (1.00) | MCL1MEN1KMT2AERAP1TDP1 | |
| SCHEMBL2552748 | 0.75 | MCL1 (1.00) | MCL1MEN1KMT2AERAP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9677115-B2 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. (US) | 2017-06-13 | — | — | US | disclosed |
| US-20130252268-A1 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. (US) | 2013-09-26 | — | — | US | disclosed |
| US-8460862-B2 | Enzyme substrates for visualizing acidic organelles | Marker Gene Technologies (US) | 2013-06-11 | — | — | US | disclosed |
| US-20100233744-A1 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. | 2010-09-16 | — | — | US | disclosed |