Terephthalamide

Terephthalamide

SCHEMBL28128192

NC(=O)c1ccc(C(N)=O)cc1.Nc1ccccc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.71
PARP1 P09874 2/20 0.71
POLB P06746 1/20 0.71
CYP3A4 P08684 1/20 0.71
MAPT P10636 1/20 0.71
CYP2C19 P33261 1/20 0.71
RECQL P46063 1/20 0.71
BLM P54132 1/20 0.71
PMP22 Q01453 1/20 0.71
HSD17B10 Q99714 1/20 0.71
TDP1 Q9NUW8 1/20 0.71
L3MBTL1 Q9Y468 1/20 0.71
PARP10 Q53GL7 8/20 0.59
PLA2G10 O15496 1/20 0.59
PLA2G2A P14555 1/20 0.59
PARP15 Q460N3 2/20 0.50
PARP4 Q9UKK3 2/20 0.50
MKNK1 Q9BUB5 2/20 0.50
MKNK2 Q9HBH9 1/20 0.50
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL28319061 0.98 TSHR (0.68) TSHRPARP1POLBCYP3A4MAPT
Benzamide SCHEMBL27393070 0.95 PARP1 (0.80) TSHRPARP1POLBCYP3A4MAPT
Benzene SCHEMBL6865184 0.92 PARP10 (0.68) TSHRPARP1POLBCYP3A4MAPT
Benzene SCHEMBL28558933 0.92 PARP10 (0.68) TSHRPARP1POLBCYP3A4MAPT
Benzamide SCHEMBL27352223 0.90 TSHR (0.80) TSHRPARP1POLBCYP3A4MAPT
Biphenyl SCHEMBL28602112 0.89 CYP3A4 (0.62) TSHRPARP1POLBCYP3A4MAPT
Terephthalamide SCHEMBL437011 0.87 PARP10 (0.74) TSHRPARP1POLBCYP3A4MAPT
SCHEMBL56532 0.87 PARP10 (0.74) TSHRPARP1POLBCYP3A4MAPT
SCHEMBL7642130 0.87 PARP10 (0.74) TSHRPARP1POLBCYP3A4MAPT
Terephthalamide SCHEMBL27486747 0.87 PARP1 (0.94) TSHRPARP1POLBCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108807812-A Insulating porous layer for nonaqueous electrolyte secondary battery 住友化学株式会社 2018-11-13 CN disclosed
CN-106531940-B Nonaqueous electrolytic solution secondary battery distance piece 住友化学株式会社 2018-01-09 CN disclosed
CN-106531940-A Nonaqueous electrolyte secondary battery separator 住友化学株式会社 2017-03-22 CN disclosed