Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.68 |
| ▸ | PARP1 | P09874 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.56 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.52 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL6865184 | 1.00 | PARP10 (0.68) | PARP10PARP1CYP3A4CYP2C19MAPT | |
| Aniline SCHEMBL28319061 | 0.95 | TSHR (0.68) | PARP10PARP1CYP3A4CYP2C19MAPT | |
| SCHEMBL7642130 | 0.95 | PARP10 (0.74) | PARP10PARP1CYP3A4CYP2C19MAPT | |
| SCHEMBL56532 | 0.95 | PARP10 (0.74) | PARP10PARP1CYP3A4CYP2C19MAPT | |
| Terephthalamide SCHEMBL437011 | 0.95 | PARP10 (0.74) | PARP10PARP1CYP3A4CYP2C19MAPT | |
| Benzamide SCHEMBL27352223 | 0.92 | TSHR (0.80) | PARP10PARP1CYP3A4CYP2C19MAPT | |
| Terephthalamide SCHEMBL28128192 | 0.92 | TSHR (0.71) | PARP10PARP1CYP3A4CYP2C19MAPT | |
| Hydrochloric Acid SCHEMBL4408462 | 0.92 | PARP10 (0.71) | PARP10PARP1CYP3A4CYP2C19MAPT | |
| Water SCHEMBL6343332 | 0.92 | PARP10 (0.71) | PARP10PARP1CYP3A4CYP2C19MAPT | |
| Biphenyl SCHEMBL28602112 | 0.91 | CYP3A4 (0.62) | PARP10PARP1CYP3A4CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110240708-B | Aqueous phase synthesis covalent organic framework material and preparation method thereof | 吉林大学 | 2021-03-30 | — | — | CN | disclosed |