Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Serine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 4/20 | 0.50 |
| ▸ | GSR | P00390 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serine SCHEMBL2812861 | 1.00 | SLC1A1 (0.50) | SLC1A1GSRPTGS1SLC7A11SLC1A3 | |
| Serine SCHEMBL28051780 | 0.89 | SLC1A1 (0.54) | SLC1A1GSRPTGS1SLC7A11SLC1A3 | |
| (D)-Serine SCHEMBL43094 | 0.89 | — | — | |
| Serine SCHEMBL6929773 | 0.89 | SLC1A1 (0.59) | SLC1A1GSRPTGS1SLC7A11SLC1A3 | |
| Serine SCHEMBL6929758 | 0.89 | SLC1A1 (0.59) | SLC1A1GSRPTGS1SLC7A11SLC1A3 | |
| Serine SCHEMBL6520912 | 0.89 | SLC1A1 (0.59) | SLC1A1GSRPTGS1SLC7A11SLC1A3 | |
| Serine SCHEMBL4455818 | 0.89 | SLC1A1 (0.59) | SLC1A1GSRPTGS1SLC7A11SLC1A3 | |
| Serine SCHEMBL1332181 | 0.89 | — | — | |
| (D)-Serine SCHEMBL6038168 | 0.89 | SLC1A1 (0.59) | SLC1A1GSRPTGS1SLC7A11SLC1A3 | |
| (D)-Serine SCHEMBL6660617 | 0.89 | SLC1A1 (0.59) | SLC1A1GSRPTGS1SLC7A11SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007149142-A1 | CRYOPRESERVATION MEDIA AND MOLECULE | PETTEGREW JAY W (US) | 2007-12-27 | — | — | WO | claimed |
| US-20060257842-A1 | Cryopreservation media and molecules | PETTEGREW JAY W | 2006-11-16 | — | — | US | claimed |
| WO-1997013148-A9 | METHOD FOR MEASURING FREE RADICAL CYTOTOXIC DEGRADATION | — | 1997-11-06 | — | — | WO | claimed |
| WO-1997013148-A1 | METHOD FOR MEASURING FREE RADICAL CYTOTOXIC DEGRADATION | STANINGER HILDEGARDE L A (US) | 1997-04-10 | — | — | WO | claimed |
| CN-111432654-A | Method for producing protein phospholipid complex from crustacean capture | 雾凇科技有限公司 | 2020-07-17 | — | — | CN | disclosed |
| CN-110314521-A | A kind of amino acid anionic functionalized ion liquid trapping nitric oxide and regenerated process | 北京化工大学 | 2019-10-11 | — | — | CN | disclosed |
| US-8273526-B2 | Method of isolating stem and progenitor cells from placenta | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) | 2012-09-25 | — | — | US | disclosed |
| US-20100248206-A1 | Method of Isolating Stem and Progenitor Cells From Placenta | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND | 2010-09-30 | — | — | US | disclosed |
| EP-2164953-A1 | METHOD OF ISOLATING STEM AND PROGENITOR CELLS FROM PLACENTA | Children's Hospital & Research Center at Oakland (US) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008156659-A1 | METHOD OF ISOLATING STEM AND PROGENITOR CELLS FROM PLACENTA | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) | 2008-12-24 | — | — | WO | disclosed |
| WO-2007149142-A1 | CRYOPRESERVATION MEDIA AND MOLECULE | PETTEGREW JAY W (US) | 2007-12-27 | — | — | WO | disclosed |
| US-20060257842-A1 | Cryopreservation media and molecules | PETTEGREW JAY W | 2006-11-16 | — | — | US | disclosed |
| WO-1997013148-A9 | METHOD FOR MEASURING FREE RADICAL CYTOTOXIC DEGRADATION | — | 1997-11-06 | — | — | WO | disclosed |
| WO-1997013148-A9 | METHOD FOR MEASURING FREE RADICAL CYTOTOXIC DEGRADATION | — | 1997-11-06 | — | — | WO | disclosed |
| WO-1997013148-A1 | METHOD FOR MEASURING FREE RADICAL CYTOTOXIC DEGRADATION | STANINGER HILDEGARDE L A (US) | 1997-04-10 | — | — | WO | disclosed |
| WO-1997013148-A1 | METHOD FOR MEASURING FREE RADICAL CYTOTOXIC DEGRADATION | STANINGER HILDEGARDE L A (US) | 1997-04-10 | — | — | WO | disclosed |
| US-4049837-A | Chill prevention for banana underpeel | CATALYTIC GENERATORS, INC. (US) | 1977-09-20 | — | — | US | disclosed |