SCHEMBL28129152

SCHEMBL28129152

NCc1ncnc(-c2ccccc2)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 1/20 0.46
PDGFRB P09619 1/20 0.46
GSK3A P49840 1/20 0.46
CDK9 P50750 1/20 0.46
CDK5 Q00535 1/20 0.46
ACVR1 Q04771 1/20 0.46
CDK5R1 Q15078 1/20 0.46
TAOK1 Q7L7X3 1/20 0.46
DYRK1B Q9Y463 1/20 0.46
DPP4 P27487 4/20 0.43
ADORA2A P29274 3/20 0.41
ADORA1 P30542 3/20 0.41
ADORA3 P0DMS8 2/20 0.41
ADORA2B P29275 2/20 0.41
POLB P06746 1/20 0.41
NOTUM Q6P988 3/20 0.40
NR1H4 Q96RI1 1/20 0.38
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
MAPK1 P28482 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27082176 0.81 L3MBTL1 (0.41) CSF1RPDGFRBGSK3ACDK9CDK5
SCHEMBL12951259 0.79 DPP4 (0.53) DPP4ADORA2AADORA1ADORA3ADORA2B
SCHEMBL27800091 0.79 TAAR1 (0.61) CSF1RPDGFRBGSK3ACDK9CDK5
SCHEMBL56387 0.79 L3MBTL1 (0.54) ADORA2AADORA1ADORA3ADORA2BPOLB
Ammonia Solution, Strong SCHEMBL28360184 0.77 L3MBTL1 (0.52) ADORA2AADORA1ADORA3ADORA2BPOLB
SCHEMBL23008430 0.74 NPC1 (0.52) ADORA2AADORA1ADORA3ADORA2BPOLB
SCHEMBL13719392 0.74 NPC1 (0.52) ADORA2AADORA1ADORA3ADORA2BPOLB
SCHEMBL16922581 0.74 NPC1 (0.52) ADORA2AADORA1ADORA3ADORA2BPOLB
SCHEMBL23008279 0.74 NPC1 (0.52) ADORA2AADORA1ADORA3ADORA2BPOLB
SCHEMBL30375151 0.74 NPC1 (0.52) ADORA2AADORA1ADORA3ADORA2BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106715560-A Use of organic oxyimides as radical generators in plastics, method for generating radicals in plastics and use of said method 弗劳恩霍弗应用研究促进协会 2017-05-24 CN disclosed
CN-106459255-A Copolymers or polymers containing oxygen imides as flame retardants for plastics materials 弗劳恩霍夫应用研究促进协会 2017-02-22 CN disclosed
CN-102112497-A Photoinitiator mixtures BASF SE 2011-06-29 CN disclosed
CN-1326447-A Process for preparing triazines with a combination of a lewis acid and a reaction promoter CYTEC TECH CORP (US) 2001-12-12 CN disclosed
CN-1228450-A Stabilisers and anti-ozonants for elastomers CIBA SC HOLDING AG (CH) 1999-09-15 CN disclosed