Isopropylbenzene

Isopropylbenzene

SCHEMBL28129337

CC(C)c1ccccc1.CCNC(=N)N

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
PKM P14618 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
AOC3 Q16853 2/20 0.39
BCAT2 O15382 1/20 0.39
TAAR1 Q96RJ0 2/20 0.38
LMNA P02545 2/20 0.38
ALDH1A1 P00352 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MAPT P10636 2/20 0.38
HTT P42858 2/20 0.38
GAA P10253 1/20 0.38
NOS3 P29474 1/20 0.38
NOS2 P35228 1/20 0.38
CNR2 P34972 1/20 0.37
KDM4E B2RXH2 2/20 0.37
ADRA2A P08913 1/20 0.37
ADRA2C P18825 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL28129348 0.81 TSHR (0.42) PKMMEN1KMT2ALMNAALDH1A1
Isopropylbenzene SCHEMBL27970219 0.80 ADRA2A (0.48) PKMAOC3TAAR1LMNAALDH1A1
Chlorobenzene SCHEMBL28128879 0.80 TSHR (0.41) KMT2ATAAR1LMNAALDH1A1MAPT
Fluorobenzene SCHEMBL28128810 0.78 GAA (0.37) PKMMEN1KMT2AALDH1A1L3MBTL1
O-Xylene SCHEMBL29074374 0.77 TSHR (0.42) PKMTAAR1ALDH1A1L3MBTL1MAPT
Fluorobenzene SCHEMBL28840059 0.76 IDO1 (0.38) PKMMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL4018230 0.76 AOC3 (0.58) AOC3BCAT2TAAR1
SCHEMBL17198959 0.76 AOC3 (0.58) AOC3BCAT2TAAR1
O-Xylene SCHEMBL29074411 0.76 TSHR (0.40) PKMKMT2AALDH1A1L3MBTL1MAPT
Hydrochloric Acid SCHEMBL28129394 0.75 TAAR1 (0.56) AOC3BCAT2TAAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106458868-A Guanidine compounds and uses thereof 伊谬诺米特医疗有限公司 2017-02-22 CN claimed
CN-106458868-A Guanidine compounds and uses thereof 伊谬诺米特医疗有限公司 2017-02-22 CN disclosed