Methane

Methane

SCHEMBL28129673

C.OC1CCCC(c2ccccc2)C1

nearest known ligand 0.53

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Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 10/20 0.53
AKR1C3 P42330 1/20 0.47
AKR1C1 Q04828 1/20 0.47
ESR2 Q92731 1/20 0.47
SLC18A3 Q16572 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16543143 0.98 CNR2 (0.54) CNR2AKR1C3AKR1C1ESR2SLC18A3
SCHEMBL31146809 0.98 CNR2 (0.54) CNR2AKR1C3AKR1C1ESR2SLC18A3
SCHEMBL787976 0.98 CNR2 (0.54) CNR2AKR1C3AKR1C1ESR2SLC18A3
SCHEMBL16543130 0.98 CNR2 (0.54) CNR2AKR1C3AKR1C1ESR2SLC18A3
SCHEMBL17730101 0.85 AKR1C3 (0.57) AKR1C3AKR1C1ESR2SLC18A3
SCHEMBL17730099 0.85 AKR1C3 (0.57) AKR1C3AKR1C1ESR2SLC18A3
SCHEMBL924589 0.85 AKR1C3 (0.57) AKR1C3AKR1C1ESR2SLC18A3
SCHEMBL780234 0.83 AKR1C3 (0.52) AKR1C3AKR1C1SLC18A3
SCHEMBL6404297 0.81 ESR2 (0.57) ESR2SLC18A3
Bicarbonate SCHEMBL7568966 0.79 AKR1C3 (0.60) AKR1C3AKR1C1SLC18A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106560470-A Oxapium iodide preparation method 平光制药股份有限公司 2017-04-12 CN claimed
CN-106560470-A Oxapium iodide preparation method 平光制药股份有限公司 2017-04-12 CN disclosed