Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.57 |
| ▸ | SLC18A3 | Q16572 | 11/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL2352938 | 0.91 | SLC18A3 (0.58) | SLC18A3SIGMAR1CYP2D6TSHRSMN1; SMN2 | |
| Hydrogen Peroxide SCHEMBL42934 | 0.88 | SLC18A3 (0.61) | SLC18A3SIGMAR1CYP2D6TSHRSMN1; SMN2 | |
| Hydrogen Peroxide SCHEMBL2352896 | 0.88 | SLC18A3 (0.61) | SLC18A3SIGMAR1CYP2D6TSHRSMN1; SMN2 | |
| Hydrogen Peroxide SCHEMBL9997756 | 0.88 | SLC18A3 (0.61) | SLC18A3SIGMAR1CYP2D6TSHRSMN1; SMN2 | |
| Hydrogen Peroxide SCHEMBL11586135 | 0.88 | SLC18A3 (0.61) | SLC18A3SIGMAR1CYP2D6TSHRSMN1; SMN2 | |
| Hydrogen Peroxide SCHEMBL5901852 | 0.88 | SLC18A3 (0.61) | SLC18A3SIGMAR1CYP2D6TSHRSMN1; SMN2 | |
| SCHEMBL42580 | 0.88 | SLC18A3 (0.61) | SLC18A3SIGMAR1CYP2D6TSHRSMN1; SMN2 | |
| SCHEMBL557667 | 0.86 | ESR2 (0.64) | ESR2SLC18A3SIGMAR1CYP2D6TSHR | |
| SCHEMBL2778652 | 0.86 | ESR2 (0.64) | ESR2SLC18A3SIGMAR1CYP2D6TSHR | |
| SCHEMBL6583115 | 0.86 | ESR2 (0.64) | ESR2SLC18A3SIGMAR1CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949585-B2 | Cyclooctanone derivatives and cyclodecanone derivative, and use thereof | EISAI CO., LTD. (JP) | 2005-09-27 | — | — | US | disclosed |
| US-20040082805-A1 | Cyclooctanone derivatives and cyclodecanone derivative, and use thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1375465-A9 | CYCLOOCTANONE DERIVATIVE AND CYCLODECANONE DERIVATIVE, AND USE THEREOF | Eisai Co., Ltd. (JP) | 2004-04-14 | — | — | EP | disclosed |
| EP-1375479-A1 | PYRROLIDINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | Eisai Co., Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082805-A1 | Cyclooctanone derivatives and cyclodecanone derivative, and use thereof | CCR1, CCL2, CCR5 | ESR2 661/4885SLC18A3 4816/4885SIGMAR1 1365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.