Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.93 |
| ▸ | MAPT | P10636 | 7/20 | 0.93 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.93 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.93 |
| ▸ | MEN1 | O00255 | 6/20 | 0.93 |
| ▸ | ESR1 | P03372 | 6/20 | 0.93 |
| ▸ | TP53 | P04637 | 3/20 | 0.93 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.93 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.93 |
| ▸ | PGR | P06401 | 3/20 | 0.93 |
| ▸ | AR | P10275 | 3/20 | 0.93 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.93 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.93 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.93 |
| ▸ | POLB | P06746 | 1/20 | 0.93 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.93 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.93 |
| ▸ | ATM | Q13315 | 1/20 | 0.93 |
| ▸ | USP2 | O75604 | 1/20 | 0.93 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418881 | 1.00 | LMNA (0.93) | LMNAMAPTKMT2ACYP3A4MEN1 | |
| SCHEMBL7751687 | 1.00 | LMNA (0.93) | LMNAMAPTKMT2ACYP3A4MEN1 | |
| SCHEMBL1315378 | 1.00 | LMNA (0.93) | LMNAMAPTKMT2ACYP3A4MEN1 | |
| Estradiol Enanthate SCHEMBL547096 | 1.00 | LMNA (0.93) | LMNAMAPTKMT2ACYP3A4MEN1 | |
| SCHEMBL3500119 | 1.00 | LMNA (0.93) | LMNAMAPTKMT2ACYP3A4MEN1 | |
| Estradiol Undecylate SCHEMBL23728444 | 1.00 | LMNA (0.93) | LMNAMAPTKMT2ACYP3A4MEN1 | |
| Estradiol Undecylate SCHEMBL453172 | 1.00 | LMNA (0.93) | LMNAMAPTKMT2ACYP3A4MEN1 | |
| SCHEMBL11596845 | 1.00 | LMNA (0.93) | LMNAMAPTKMT2ACYP3A4MEN1 | |
| SCHEMBL17419452 | 1.00 | LMNA (0.93) | LMNAMAPTKMT2ACYP3A4MEN1 | |
| Estradiol Valerate SCHEMBL6195972 | 0.96 | LMNA (1.00) | LMNAMAPTKMT2ACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109414553-A | Method and apparatus for controlling drug evaporation | 普林斯顿大学理事会 | 2019-03-01 | — | — | CN | disclosed |
| CN-107750177-A | Use of antistatic materials in airways for hot aerosol condensation processes | 艾利斯达医药品公司 | 2018-03-02 | — | — | CN | disclosed |
| CN-106455705-A | Methods and devices for smoking urge relief | 方特慕控股第私人有限公司 | 2017-02-22 | — | — | CN | disclosed |