Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.75 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.75 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.75 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.75 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.75 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.65 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.65 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.65 |
| ▸ | CFTR | P13569 | 1/20 | 0.63 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.59 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.57 |
| ▸ | ALPL | P05186 | 1/20 | 0.57 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10854933 | 0.99 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9430800 | 0.99 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL16058829 | 0.96 | PDE4A (0.77) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| Sulfuric Acid SCHEMBL29003546 | 0.93 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL21381258 | 0.87 | PDE4A (0.92) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9430425 | 0.86 | PDE4A (0.92) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9430292 | 0.86 | PDE4A (0.83) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9431257 | 0.86 | PDE4A (0.79) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL3421652 | 0.86 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7458212 | 0.86 | PDE4A (0.89) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107823410-A | A kind of Diprophylline tablet and preparation method thereof | 华益药业科技(安徽)有限公司 | 2018-03-23 | — | — | CN | claimed |
| CN-109890366-A | Combination medicine for treating cardiovascular diseases and preparation and use methods thereof | 美进医药公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-105744932-B | For treating the composition comprising Torasemide and Baclofen of neurological disorder | 法耐斯特公司 | 2019-01-08 | — | — | CN | disclosed |
| CN-109071493-A | Pesticidally active heterocyclic derivatives with sulphur containing substituents | 先正达参股股份有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-107157964-A | Coordinate the Foradil Aerolizer formoterol fumarate and its preparation and application of pollen shape carbohydrate carrier | 谭淞文 | 2017-09-15 | — | — | CN | disclosed |
| CN-104098567-B | Diprophylline crystalline substance II types material and preparation method and its pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2017-07-28 | — | — | CN | disclosed |
| CN-106715428-A | Pesticidally active tetracyclic derivatives with sulphur containing substituents | 先正达参股股份有限公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-106604922-A | Pesticidally active heterocyclic derivatives with sulphur containing substituents | 先正达参股股份有限公司 | 2017-04-26 | — | — | CN | disclosed |
| CN-106573891-A | Pesticidally active heterocyclic derivatives with sulphur containing substituents | 先正达参股股份有限公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-106488914-A | Tool with sulfur-bearing substituent kills harmful organism active heterocycles derivative | 先正达参股股份有限公司 | 2017-03-08 | — | — | CN | disclosed |