Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.63 |
| ▸ | APP | P05067 | 5/20 | 0.51 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29880282 | 1.00 | LTA4H (0.63) | LTA4HAPPIDO1SLC5A1SLC5A2 | |
| SCHEMBL10970519 | 0.87 | LTA4H (0.76) | LTA4HIDO1SLC5A1SLC5A2SAE1 | |
| SCHEMBL14191204 | 0.83 | LTA4H (0.70) | LTA4HIDO1MTNR1AMTNR1BKDM4E | |
| SCHEMBL5250014 | 0.83 | APP (0.53) | LTA4HAPPIDO1SMN1; SMN2RAB9A | |
| SCHEMBL4507875 | 0.83 | APP (0.53) | LTA4HAPPIDO1SMN1; SMN2RAB9A | |
| SCHEMBL9348618 | 0.81 | IDO1 (0.50) | APPIDO1SMN1; SMN2RAB9A | |
| SCHEMBL4314726 | 0.81 | APP (0.68) | LTA4HAPPIDO1SAE1UBA2 | |
| SCHEMBL9352538 | 0.80 | IDO1 (0.58) | IDO1SMN1; SMN2RAB9A | |
| SCHEMBL20418385 | 0.80 | LTA4H (0.66) | LTA4HIDO1SLC5A1SLC5A2KDM4E | |
| SCHEMBL20691033 | 0.79 | IDO1 (0.46) | LTA4HIDO1SLC5A2SAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110015952-B | Diaryl methane compound and preparation method and application thereof | 北京大学深圳研究生院 | 2022-08-19 | — | — | CN | disclosed |
| CN-106478326-A | The synthetic method of one class diarylmethanes | 北京大学 | 2017-03-08 | — | — | CN | disclosed |