Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479374 | 0.79 | RET (0.35) | MEN1KMT2ASLC6A3SLC6A2CYP2D6 | |
| SCHEMBL10609155 | 0.79 | RET (0.35) | MEN1KMT2ASLC6A3SLC6A2CYP2D6 | |
| SCHEMBL5025415 | 0.77 | CYP2A6 (0.33) | CYP2A6CYP1A2HSP90AA1PAX8SLC6A3 | |
| SCHEMBL10878544 | 0.75 | TDP1 (0.31) | CYP2A6SLC6A3SLC6A2SLC6A4TDP1 | |
| SCHEMBL28244256 | 0.74 | SLC6A2 (0.33) | CYP2A6CYP1A2HSP90AA1PAX8MEN1 | |
| SCHEMBL1313656 | 0.74 | CYP1A2 (0.33) | CYP1A2HSP90AA1PAX8MEN1KMT2A | |
| SCHEMBL25549138 | 0.74 | ALDH1A1 (0.33) | SLC6A3SLC6A2SLC6A4CYP2D6KCNH2 | |
| SCHEMBL12071676 | 0.73 | — | — | |
| SCHEMBL12071045 | 0.72 | — | — | |
| SCHEMBL30758145 | 0.70 | CYP1A2 (0.41) | CYP2A6CYP1A2MEN1KMT2ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106543310-B | A kind of olefin polymerization catalyst system and its application | 中国石油化工股份有限公司 | 2019-06-28 | — | — | CN | claimed |
| CN-106543310-A | A kind of olefin polymerization catalyst system and its application | 中国石油化工股份有限公司 | 2017-03-29 | — | — | CN | claimed |
| CN-106543310-B | A kind of olefin polymerization catalyst system and its application | 中国石油化工股份有限公司 | 2019-06-28 | — | — | CN | disclosed |