Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MARK3 | P27448 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9082 | 0.87 | LMNA (0.57) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL29559610 | 0.87 | LMNA (0.57) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Water SCHEMBL27775008 | 0.85 | LMNA (0.55) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL30834859 | 0.85 | LMNA (0.55) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Hydrochloric Acid SCHEMBL11162217 | 0.85 | PI4KA (0.59) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL8716028 | 0.85 | LMNA (0.55) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL9798930 | 0.85 | LMNA (0.55) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Iodomethane SCHEMBL27477608 | 0.82 | LRRK2 (0.52) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Pyrimidine SCHEMBL27818758 | 0.81 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL15966581 | 0.79 | PI4KA (0.76) | PI4KAPI4K2BPI4K2API4KBLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106414456-B | Compounds for the prevention and treatment of neurodegenerative diseases and pain | 中央研究院 | 2018-12-14 | — | — | CN | disclosed |
| CN-106414456-A | Compounds for the prevention and treatment of neurodegenerative diseases and pain | 中央研究院 | 2017-02-15 | — | — | CN | disclosed |