Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | FAP | Q12884 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14655442 | 1.00 | DPP4 (0.51) | DPP4DPP8DPP9DPP7FAP | |
| Trifluoroacetic Acid SCHEMBL14738523 | 0.91 | DPP4 (0.45) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL15203437 | 0.87 | DPP4 (0.54) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL15203541 | 0.87 | DPP4 (0.54) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL15203546 | 0.85 | DPP4 (0.58) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL15203468 | 0.85 | DPP4 (0.58) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL14655934 | 0.85 | DPP4 (0.58) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL2456457 | 0.83 | DPP4 (0.56) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL2456462 | 0.83 | DPP4 (0.56) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9901341 | 0.81 | DPP4 (0.50) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104024258-B | Pyrrolopyrazine kinase inhibitors | 霍夫曼-拉罗奇有限公司 | 2017-02-15 | — | — | CN | disclosed |