Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA4 | P22748 | 5/20 | 0.37 |
| ▸ | CA6 | P23280 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146270 | 0.86 | NPC1 (0.43) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL2436086 | 0.83 | NPC1 (0.41) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL2302905 | 0.83 | NPC1 (0.41) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3823075 | 0.82 | NPC1 (0.43) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11669057 | 0.80 | KDM4E (0.50) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11058566 | 0.80 | KDM4E (0.50) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL1986958 | 0.79 | NPC1 (0.45) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3823307 | 0.78 | NPC1 (0.43) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL444967 | 0.77 | NPC1 (0.39) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL42517 | 0.77 | NPC1 (0.49) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678788-A | A kind of 1,2- diaryl indoles, derivative and its synthetic method | 湘潭大学 | 2019-04-26 | — | — | CN | claimed |
| CN-104177298-B | Bis- substitution -4,5- dihydros -1H of 4,4--imidazoles -5- ketone, derivative and its synthetic method | 湘潭大学 | 2018-10-02 | — | — | CN | claimed |
| CN-106117113-B | Polysubstituted carbazole, derivative and its synthetic method | 湘潭大学 | 2019-08-16 | — | — | CN | disclosed |
| CN-109678788-A | A kind of 1,2- diaryl indoles, derivative and its synthetic method | 湘潭大学 | 2019-04-26 | — | — | CN | disclosed |
| CN-105658685-B | β Chinese celery alkene polymer, its manufacturing method and formed products | 国立大学法人名古屋大学 | 2019-04-05 | — | — | CN | disclosed |
| CN-108929251-A | Method for direct trifluoromethylation of C (sp3) -H | 南京工业大学 | 2018-12-04 | — | — | CN | disclosed |
| CN-108883103-A | PIPERIDINYL NOCICEPTIN RECEPTOR COMPOUNDS | 阿斯特来亚治疗有限责任公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-107922543-A | Copolymer, its manufacture method, electric wire coatings resin material and electric wire | 旭硝子株式会社 | 2018-04-17 | — | — | CN | disclosed |
| CN-107735730-A | developing solution, pattern forming method and manufacturing method of electronic device | 富士胶片株式会社 | 2018-02-23 | — | — | CN | disclosed |
| CN-106661012-A | Carboxamide derivatives | 诺华股份有限公司 | 2017-05-10 | — | — | CN | disclosed |