Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823075 | 0.95 | NPC1 (0.43) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3817862 | 0.89 | NPC1 (0.46) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11058566 | 0.81 | KDM4E (0.50) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL7146270 | 0.80 | NPC1 (0.43) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL31619444 | 0.78 | NPC1 (0.47) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11413672 | 0.78 | NPC1 (0.47) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3823777 | 0.78 | CA1 (0.45) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL4740933 | 0.78 | NPC1 (0.47) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3818006 | 0.78 | KDM4E (0.46) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| Hydrogen Peroxide SCHEMBL28783701 | 0.78 | NPC1 (0.47) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383834-B2 | Process for preparing unsaturated lactones | SYMRISE AG (DE) | 2013-02-26 | — | — | US | disclosed |
| US-20090306411-A1 | PROCESS FOR PREPARING UNSATURATED LACTONES | SYMRISE GMBH & CO. KG (DE) | 2009-12-10 | — | — | US | disclosed |
| WO-2005113533-A9 | PROCESS FOR PREPARING UNSATURATED LACTONES | SYMRISE GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |
| EP-1747211-B1 | PROCESS FOR PREPARING UNSATURATED LACTONES | SYMRISE GMBH & CO KG (DE) | 2009-08-26 | — | — | EP | disclosed |
| EP-1747211-A1 | PROCESS FOR PREPARING UNSATURATED LACTONES | Akzo Nobel N.V. (NL) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005113533-A1 | PROCESS FOR PREPARING UNSATURATED LACTONES | SYMRISE GMBH & CO. KG (DE) | 2005-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306411-A1 | PROCESS FOR PREPARING UNSATURATED LACTONES | ALOX5, ALOX12, ALOX15 | NPC1 4002/4885RAB9A 4377/4885GAA 1928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.