Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GPR3 | P46089 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955313 | 0.86 | AHR (0.45) | AHRMAPTMEN1KMT2AKIF11 | |
| SCHEMBL9471066 | 0.83 | AHR (0.43) | AHRMAPTMEN1KMT2AKIF11 | |
| SCHEMBL14519076 | 0.83 | GSK3B (0.53) | AHRMAPTMEN1KMT2AKIF11 | |
| SCHEMBL5636833 | 0.82 | MEN1 (0.46) | AHRMAPTMEN1KMT2AKIF11 | |
| SCHEMBL5636837 | 0.82 | MEN1 (0.46) | AHRMAPTMEN1KMT2AKIF11 | |
| SCHEMBL528428 | 0.78 | MEN1 (0.70) | AHRMAPTMEN1KMT2AKIF11 | |
| SCHEMBL2907190 | 0.78 | AHR (0.47) | AHRMAPTMEN1KMT2AKIF11 | |
| SCHEMBL248974 | 0.78 | HPGD (0.61) | AHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5780430 | 0.78 | AHR (0.47) | AHRMAPTMEN1KMT2AKIF11 | |
| SCHEMBL1163942 | 0.78 | MAPT (0.55) | MAPTMEN1KMT2AKIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114318375-B | Indolo [2,3-A ] carbazole and preparation method thereof | 中钢集团南京新材料研究院有限公司 | 2023-04-11 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-114318375-A | Indolo [2,3-A ] carbazole and preparation method thereof | 中钢集团南京新材料研究院有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-106631973-A | Method for synthesizing 2,4-dialkylene-substituted indole compound with one-pot process | 浙江大学 | 2017-05-10 | — | — | CN | disclosed |
| CN-103664973-B | Spiro-oxindole compounds and their use as therapeutic agents | 泽农医药公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-104945302-B | The structure of the double Schiff bases of 3 indolecarboxaldehyde of benzil dihydrazone, preparation and use | 齐鲁工业大学 | 2017-04-05 | — | — | CN | disclosed |