Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245129 | 0.96 | SLC6A4 (0.38) | SLC6A4HTR6GRIA2HTR2CHTR2B | |
| SCHEMBL28135474 | 0.94 | SLC6A4 (0.37) | SLC6A4HTR6GRIA2HTR2CHTR2B | |
| SCHEMBL28135432 | 0.79 | GRIA2 (0.32) | SLC6A4HTR6GRIA2 | |
| SCHEMBL16345371 | 0.79 | SLC6A4 (0.36) | SLC6A4HTR6GRIA2HTR2CHTR2B | |
| SCHEMBL19681453 | 0.78 | — | — | |
| SCHEMBL12648424 | 0.75 | SLC6A4 (0.35) | SLC6A4HTR6GRIA2HTR2CHTR2B | |
| SCHEMBL19734402 | 0.74 | SLC6A4 (0.35) | SLC6A4HTR6GRIA2HTR2CHTR2B | |
| SCHEMBL12648514 | 0.74 | SLC6A4 (0.35) | SLC6A4HTR6GRIA2HTR2CHTR2B | |
| SCHEMBL1602688 | 0.74 | SLC6A4 (0.37) | SLC6A4HTR6GRIA2HTR2CHTR2B | |
| SCHEMBL9224957 | 0.74 | ALDH1A1 (0.42) | SLC6A4HTR6HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928247-A | Spiral shell oxindole compounds and its purposes as therapeutic agent | 泽农医药公司 | 2017-07-07 | — | — | CN | disclosed |
| CN-103664973-B | Spiro-oxindole compounds and their use as therapeutic agents | 泽农医药公司 | 2017-04-19 | — | — | CN | disclosed |