Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL2199525 | 0.84 | NOTUM (0.50) | NPC1RAB9AKDM4EALDH1A1CYP19A1 | |
| Biphenyl SCHEMBL27870612 | 0.82 | NOTUM (0.48) | NPC1RAB9AKDM4EALDH1A1CYP19A1 | |
| SCHEMBL9152375 | 0.78 | CA4 (0.68) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| Biphenyl SCHEMBL11784329 | 0.78 | CA4 (0.68) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL291776 | 0.78 | CA4 (0.68) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL17283658 | 0.78 | CA4 (0.68) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| Water SCHEMBL1023367 | 0.75 | CA4 (0.65) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| Water SCHEMBL3540832 | 0.75 | CA4 (0.65) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL28478235 | 0.75 | CA4 (0.65) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL29220727 | 0.75 | CA4 (0.65) | NPC1RAB9AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104761536-B | Method of synthesizing 2-substituted benzothiazole-type derivative | 内蒙古工业大学 | 2017-05-10 | — | — | CN | claimed |