Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067284 | 0.79 | MEN1 (0.40) | MEN1KMT2ATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL5796284 | 0.79 | MEN1 (0.40) | MEN1KMT2ATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL28137090 | 0.78 | TSHR (0.34) | MEN1KMT2ATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL28322920 | 0.76 | MEN1 (0.38) | MEN1KMT2ATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL28264384 | 0.74 | P2RX4 (0.33) | MEN1KMT2ATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL28264402 | 0.73 | — | — | |
| SCHEMBL28263284 | 0.67 | — | — | |
| SCHEMBL5174448 | 0.64 | MEN1 (0.36) | MEN1KMT2ATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL27700833 | 0.64 | — | — | |
| SCHEMBL28000955 | 0.62 | MEN1 (0.35) | MEN1KMT2ATSHRMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884453-B | Anthelmintic compounds and compositions and methods of using the same | 梅里亚股份有限公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-106536518-A | Anthelmintic compounds | 梅里亚股份有限公司 | 2017-03-22 | — | — | CN | disclosed |