SCHEMBL28136342

SCHEMBL28136342

COc1ccc2ccc(O)c(OC)c2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.51
ESR1 P03372 1/20 0.51
KDM4E B2RXH2 2/20 0.48
MEN1 O00255 2/20 0.48
ALDH1A1 P00352 2/20 0.48
MAPT P10636 2/20 0.48
KMT2A Q03164 2/20 0.48
GAA P10253 1/20 0.48
THRB P10828 1/20 0.48
RECQL P46063 1/20 0.48
BLM P54132 1/20 0.48
MCL1 Q07820 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MTNR1A P48039 4/20 0.47
MTNR1B P49286 1/20 0.47
ERN1 O75460 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2A6 P11509 1/20 0.45
MPL P40238 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29218980 0.82 MEN1 (0.50) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL1305457 0.82 KDM4E (0.50) ESR2KDM4EMEN1ALDH1A1MAPT
SCHEMBL29493121 0.82 ESR1 (0.62) ESR2ESR1KDM4EMEN1ALDH1A1
SCHEMBL2187208 0.82 ESR1 (0.62) ESR2ESR1KDM4EMEN1ALDH1A1
SCHEMBL31686262 0.79 KDM4E (0.56) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL3188467 0.79 CYP17A1 (0.55) ESR2ESR1KDM4EMEN1ALDH1A1
SCHEMBL28795649 0.79 POLB (0.50) ESR2ESR1KDM4EMEN1ALDH1A1
SCHEMBL12486732 0.79 ESR1 (0.54) ESR2ESR1KDM4EMEN1ALDH1A1
SCHEMBL31570914 0.79 ESR1 (0.54) ESR2ESR1KDM4EMEN1ALDH1A1
SCHEMBL19382614 0.79 CYP1A2 (0.61) KDM4EMEN1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106536518-A Anthelmintic compounds 梅里亚股份有限公司 2017-03-22 CN disclosed