Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL5874295 | 0.92 | CA12 (0.65) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL10791213 | 0.92 | CA12 (0.65) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL10791210 | 0.92 | CA12 (0.65) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL27280139 | 0.90 | CA12 (0.61) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL28217458 | 0.90 | CA12 (0.61) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL27919347 | 0.89 | CA12 (0.69) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL27874791 | 0.87 | CA12 (0.73) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL27762777 | 0.86 | CA12 (0.50) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL15396 | 0.84 | — | — | |
| Phenol SCHEMBL28441213 | 0.84 | CA12 (0.79) | TDP1CA12CA1CA2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106795258-B | Phenolic hydroxy group resin, preparation method, photonasty or solidification compound, erosion resistant, film, solidfied material and resist lower membrane | DIC株式会社 | 2019-11-08 | — | — | CN | disclosed |
| CN-105392765-B | Compound, photosensitive composite, resist composition, resist film, solidification compound, resist composition for underlayer film and the resist lower membrane of phenolic hydroxy group | DIC株式会社 | 2018-03-02 | — | — | CN | disclosed |
| CN-106795258-A | Phenolic hydroxy group resin, preparation method, photonasty or solidification compound, erosion resistant, film, solidfied material and resist lower membrane | DIC株式会社 | 2017-05-31 | — | — | CN | disclosed |
| CN-106433019-A | Carbon fiber felt lamination sheet and preparation method thereof | 四川东材科技集团股份有限公司 | 2017-02-22 | — | — | CN | disclosed |