Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA3 | P07451 | 2/20 | 0.65 |
| ▸ | CA4 | P22748 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL10791210 | 1.00 | CA12 (0.65) | CA12CA1CA2CA3CA4 | |
| Phenol SCHEMBL10791213 | 1.00 | CA12 (0.65) | CA12CA1CA2CA3CA4 | |
| Phenol SCHEMBL28217458 | 0.97 | CA12 (0.61) | CA12CA1CA2CA3CA4 | |
| Phenol SCHEMBL27280139 | 0.97 | CA12 (0.61) | CA12CA1CA2CA3CA4 | |
| Phenol SCHEMBL27919347 | 0.97 | CA12 (0.69) | CA12CA1CA2CA3CA4 | |
| Phenol SCHEMBL28136426 | 0.92 | TDP1 (0.55) | CA12CA1CA2CA3CA4 | |
| Phenol SCHEMBL1793331 | 0.89 | CA12 (0.58) | CA12CA1CA2CA3CA4 | |
| Phenol SCHEMBL27762777 | 0.88 | CA12 (0.50) | CA12CA1CA2CA3CA4 | |
| Phenol SCHEMBL5875014 | 0.87 | CA12 (0.55) | CA12CA1CA2CA3CA4 | |
| Phenol SCHEMBL28094966 | 0.86 | CA12 (0.48) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110429279-A | A kind of organic positive electrode of lithium ion battery and its application | UNIV HUAZHONG SCIENCE TECH | 2019-11-08 | — | — | CN | claimed |
| CN-110396195-A | A kind of polyarylsulfone (PAS) quasi polymer and preparation method thereof containing reduction phenol piperazine structure | UNIV JILIN | 2019-11-01 | — | — | CN | claimed |
| CN-109913191-A | A kind of water base micro-capsule sand washing composition of high sulfur gas wells, the water base micro-capsule sand cleaning fluid of high sulfur gas wells | 中国石油化工股份有限公司 | 2019-06-21 | — | — | CN | claimed |
| CN-109400844-A | A kind of biology base photocurable prepolymer and preparation method thereof | 江苏三木化工股份有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-109180593-A | Phenol piperazine alkaloids secondary metabolite and its application | 云南大学 | 2019-01-11 | — | — | CN | claimed |
| CN-108658992-A | A kind of indoles and phenol piperazine compound and application thereof and luminescent device | 上海道亦化工科技有限公司 | 2018-10-16 | — | — | CN | claimed |
| CN-108254341-A | Double quantum dot fluorescent two-dimensional probe malathion and ethion identification quantitative detection method and device | 安徽大学 | 2018-07-06 | — | — | CN | claimed |
| CN-107236108-A | The preparation method of aqueous polyurethane acrylate | 江苏三木化工股份有限公司 | 2017-10-10 | — | — | CN | claimed |
| CN-104212852-B | A kind of phenol piperazine class antitumor antibiotics and preparation method thereof | 云南大学 | 2017-07-28 | — | — | CN | claimed |
| CN-106892903-A | Organic electroluminescent compounds and its luminescent device based on phenol piperazine and carbazole | 上海道亦化工科技有限公司 | 2017-06-27 | — | — | CN | claimed |
| CN-104557728-B | Method for preparing carbendazol from o-phenylenediamine rectification residues | 江苏扬农化工集团有限公司 | 2017-05-03 | — | — | CN | claimed |
| CN-103992324-B | A kind of phenol piperazine acceptor molecule based on naphthyl and the synthesis of reagent paper and identifying Fe3+and H2pO4-in application | 西北师范大学 | 2016-08-17 | — | — | CN | claimed |
| CN-104212852-A | Phenazine antitumor antibiotic and preparation method thereof | UNIV YUNNAN | 2014-12-17 | — | — | CN | claimed |
| CN-103992324-A | Naphthyl-based phenazine receptor molecule, test paper and synthesis thereof, and application of receptor molecule in identification of Fe<3+> and H2PO4<-> | UNIV NORTHWEST NORMAL | 2014-08-20 | — | — | CN | claimed |
| CN-101173892-B | Fingerprint identification method for tegillarca granosa in different sea area | UNIV NINGBO | 2010-10-13 | — | — | CN | claimed |
| CN-101511902-A | Konjugierte polymere, deren darstellung und verwendung | MERCK PATENT GMBH (DE) | 2009-08-19 | — | — | CN | claimed |
| CN-101080477-A | Electroluminescent polymers and their use | MERCK PATENT GMBH (DE) | 2007-11-28 | — | — | CN | claimed |
| CN-1294519-A | Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient | INPHARMA SA (CH) | 2001-05-09 | — | — | CN | claimed |
| CN-107674052-B | Synthesis method of vilazodone intermediate 5- (1-piperazinyl) -2-benzofuran-2-carboxylic acid ethyl ester | 连云港恒运药业有限公司 | 2021-03-05 | — | — | CN | disclosed |
| CN-1050105-A | Making contains the method for the optically-readable media of embossed information | DU PONT (US) | 1991-03-20 | — | — | CN | disclosed |