Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585755 | 0.81 | ADRA2A (0.49) | FDFT1SLC6A2SLC6A4SLC6A3CYP11B1 | |
| Hydrochloric Acid SCHEMBL2714669 | 0.79 | ADRA2A (0.51) | FDFT1SLC6A2SLC6A4SLC6A3EDNRA | |
| SCHEMBL16943126 | 0.79 | MAPT (0.43) | FDFT1SLC6A2SLC6A4SLC6A3CYP11B1 | |
| SCHEMBL23579386 | 0.78 | FDFT1 (0.41) | FDFT1SLC6A2SLC6A4SLC6A3CYP11B1 | |
| SCHEMBL25687977 | 0.78 | FDFT1 (0.45) | FDFT1SLC6A2SLC6A4SLC6A3CYP11B1 | |
| SCHEMBL17653972 | 0.76 | CDK1 (0.42) | FDFT1SLC6A2SLC6A4SLC6A3CYP11B1 | |
| Hydrochloric Acid SCHEMBL1871520 | 0.76 | FDFT1 (0.44) | FDFT1SLC6A2SLC6A4SLC6A3ADRA2A | |
| Hydrochloric Acid SCHEMBL25431317 | 0.76 | STK17A (0.40) | FDFT1ADRA2AADRA2BADRA2CFPR2 | |
| SCHEMBL2169939 | 0.76 | FDFT1 (0.40) | FDFT1SLC6A2SLC6A4SLC6A3CYP11B1 | |
| SCHEMBL2171131 | 0.75 | RRM2 (0.47) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104781250-B | New antibacterial compounds | 爱尔兰詹森科学公司 | 2017-05-10 | — | — | CN | disclosed |