Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84741 | 0.83 | — | — | |
| Pyridine SCHEMBL28122960 | 0.79 | TDP1 (0.37) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL28273786 | 0.77 | ALDH1A1 (0.44) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL28329116 | 0.74 | TSHR (0.70) | TSHRNAPRTTDP1GAA | |
| Pyridine SCHEMBL28092920 | 0.74 | TSHR (0.39) | TSHRNAPRTTDP1PPARA | |
| SCHEMBL21613918 | 0.72 | TSHR (0.65) | TSHRNAPRTTDP1GAA | |
| Pyridine SCHEMBL27854287 | 0.69 | TSHR (0.39) | TSHRNAPRTTDP1PPARA | |
| Pyridine SCHEMBL28312018 | 0.69 | TDP1 (0.39) | TSHRNAPRTTDP1PPARA | |
| Pyridine SCHEMBL28074890 | 0.69 | TSHR (0.39) | TSHRNAPRTTDP1PPARA | |
| Pyridine SCHEMBL28102591 | 0.69 | TDP1 (0.39) | TSHRNAPRTTDP1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206427-A | Aromatic heterocycle vinyl Pyrazolopyrimidines, pharmaceutical preparation and preparation method and application | 安徽医科大学 | 2019-01-15 | — | — | CN | claimed |
| CN-108175860-A | A kind of poly curcumin thio-2 acid copolymer prodrug nano-micelle of esterase response type and its preparation method and application | 华南理工大学 | 2018-06-19 | — | — | CN | claimed |
| CN-106892821-A | A kind of preparation method of 3,4- bis- (2- methoxy ethoxies) ethyl benzoate | 浙江九洲药业股份有限公司 | 2017-06-27 | — | — | CN | claimed |
| CN-106881150-B | A kind of preparation method of supported 4- (N, N- dimethyl) aminopyridine catalyst | 西北大学 | 2019-11-08 | — | — | CN | disclosed |
| CN-108191812-A | Carnosic acid derivative and preparation method and application | 昆明医科大学 | 2018-06-22 | — | — | CN | disclosed |
| CN-106881150-A | A kind of preparation method of supported 4 (N, N dimethyl) aminopyridine catalyst | 西北大学 | 2017-06-23 | — | — | CN | disclosed |