Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.62 |
| ▸ | CES1 | P23141 | 2/20 | 0.62 |
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL28137774 | 0.93 | POLB (0.70) | POLBMAPK1SRD5A2CES1CES2 | |
| SCHEMBL28146457 | 0.93 | POLB (0.57) | POLBMAPK1SRD5A2CES1CES2 | |
| Hexanoate SCHEMBL27686701 | 0.93 | POLB (0.57) | POLBMAPK1SRD5A2CES1CES2 | |
| Stearic Acid SCHEMBL28224714 | 0.92 | ALDH1A1 (0.57) | POLBMAPK1SRD5A2CES1CES2 | |
| Dodecanoate SCHEMBL28158995 | 0.92 | ALDH1A1 (0.57) | POLBMAPK1SRD5A2CES1CES2 | |
| Myristic Acid SCHEMBL28224713 | 0.92 | ALDH1A1 (0.57) | POLBMAPK1SRD5A2CES1CES2 | |
| Octanoic Acid SCHEMBL27955224 | 0.92 | ALDH1A1 (0.57) | POLBMAPK1SRD5A2CES1CES2 | |
| Palmitic Acid SCHEMBL27914712 | 0.92 | ALDH1A1 (0.57) | POLBMAPK1SRD5A2CES1CES2 | |
| SCHEMBL229627 | 0.88 | POLB (0.82) | POLBMAPK1SRD5A2CES1CES2 | |
| Benzophenone SCHEMBL28231509 | 0.88 | POLB (0.82) | POLBMAPK1SRD5A2CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106879257-A | For the vaccine of streptococcus pneumonia (Streptococcus pneumoniae) Serotype8 | 马普科技促进协会 | 2017-06-20 | — | — | CN | disclosed |