Pyrazinoic Acid

Pyrazinoic Acid

SCHEMBL28138697

O=C(O)c1c[nH]c2ccccc12.O=C(O)c1cnccn1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.58
KDM4E B2RXH2 2/20 0.56
NAPRT Q6XQN6 1/20 0.56
HCAR2 Q8TDS4 1/20 0.56
GPR84 Q9NQS5 1/20 0.51
PBRM1 Q86U86 1/20 0.49
ALDH1A1 P00352 1/20 0.49
ATM Q13315 1/20 0.49
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
MAPT P10636 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
LMNA P02545 1/20 0.47
HTT P42858 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
POLB P06746 1/20 0.47
GAA P10253 1/20 0.47
NR4A2 P43354 2/20 0.47
ADAM17 P78536 1/20 0.47
CTNNB1 P35222 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21448960 0.87 GPR84 (0.61) SMN1; SMN2KDM4EGPR84PBRM1ALDH1A1
SCHEMBL1074243 0.81 SMN1; SMN2 (0.53) SMN1; SMN2KDM4EGPR84PBRM1ALDH1A1
SCHEMBL22644143 0.80 GPR84 (0.63) SMN1; SMN2GPR84PBRM1ALDH1A1ATM
SCHEMBL64182 0.80 GPR84 (0.77) KDM4EGPR84PBRM1ALDH1A1ATM
Hydrochloric Acid SCHEMBL29435427 0.78 GPR84 (0.74) KDM4EGPR84PBRM1ALDH1A1ATM
SCHEMBL29272694 0.78 GPR84 (0.74) KDM4EGPR84PBRM1ALDH1A1ATM
Hydrochloric Acid SCHEMBL7437913 0.78 GPR84 (0.74) KDM4EGPR84PBRM1ALDH1A1ATM
SCHEMBL27656464 0.78 GPR84 (0.74) KDM4EGPR84PBRM1ALDH1A1ATM
Ammonia Solution, Strong SCHEMBL27380523 0.78 GPR84 (0.74) KDM4EGPR84PBRM1ALDH1A1ATM
Hydrochloric Acid SCHEMBL28246505 0.78 GPR84 (0.74) KDM4EGPR84PBRM1ALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104208848-B golf ball 邓禄普体育用品株式会社 2017-04-12 CN disclosed