SCHEMBL28140265

SCHEMBL28140265

CC(C)C1CC(C2CCCCC2)Cc2c1ccc1c2ccc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.34
HTR2A P28223 6/20 0.32
HTR2C P28335 6/20 0.32
HTR2B P41595 6/20 0.32
HRH3 Q9Y5N1 5/20 0.32
SLC18A2 Q05940 1/20 0.32
SIGMAR1 Q99720 2/20 0.31
SLC6A2 P23975 3/20 0.31
SLC6A4 P31645 2/20 0.31
SLC6A3 Q01959 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP1A2 P05177 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
ACHE P22303 1/20 0.31
AHR P35869 1/20 0.31
METAP2 P50579 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28143760 0.84 HPRT1 (0.37) HPRT1HTR2AHTR2CHTR2BHRH3
SCHEMBL28062980 0.81 HPRT1 (0.39) HPRT1HTR2ASIGMAR1SLC6A2SLC6A4
SCHEMBL28140241 0.77 ALDH1A1 (0.40) HPRT1HRH3SLC18A2SLC6A2SLC6A4
SCHEMBL27610402 0.71 HPRT1 (0.40) HPRT1SLC6A2ALDH1A1MAPTKDM4E
SCHEMBL28140264 0.70 HPRT1 (0.39) HPRT1SLC6A2SLC6A4SLC6A3ALDH1A1
Phenanthrene SCHEMBL27694989 0.70 ALDH1A1 (0.60) HPRT1ALDH1A1MAPTKDM4ECYP1A2
SCHEMBL27360664 0.69 MAPT (0.42) HPRT1HRH3SLC6A2ALDH1A1MAPT
SCHEMBL27331555 0.69 ALDH1A1 (0.41) HPRT1HRH3SLC6A2ALDH1A1MAPT
SCHEMBL27770855 0.69 HPRT1 (0.40) HPRT1HTR2AHTR2CHTR2BHRH3
SCHEMBL8740444 0.68 HPRT1 (0.50) HPRT1SLC6A2ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104662030-B Transition metal compound, catalyst for olefin polymerization, and process for producing olefin polymer 三井化学株式会社 2017-05-17 CN disclosed
CN-104662050-B Process for producing olefin polymer and olefin polymer 三井化学株式会社 2017-03-22 CN disclosed