SCHEMBL28140348

SCHEMBL28140348

O=CC=CNCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.63
ADH1C P00326 1/20 0.63
ADH1A P07327 1/20 0.63
ADH7 P40394 1/20 0.63
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAPT P10636 4/20 0.46
ALDH1A1 P00352 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 1/20 0.46
HPGD P15428 1/20 0.46
RAB9A P51151 1/20 0.46
CA12 O43570 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA14 Q9ULX7 1/20 0.42
MAOA P21397 1/20 0.42
IDO1 P14902 2/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29798082 0.82 ADH1B (0.65) ADH1BADH1CADH1AADH7KMT2A
SCHEMBL8713797 0.82 ADH1B (0.65) ADH1BADH1CADH1AADH7KMT2A
SCHEMBL19512775 0.79 ADH1B (0.52) ADH1BADH1CADH1AADH7KMT2A
SCHEMBL8867945 0.78 ADH1B (0.68) ADH1BADH1CADH1AADH7KMT2A
SCHEMBL27354 0.78 ADH1B (1.00) ADH1BADH1CADH1AADH7KMT2A
SCHEMBL19415688 0.78 ADH1B (0.50) ADH1BADH1CADH1AADH7KMT2A
SCHEMBL24060195 0.76 ADH1B (0.58) ADH1BADH1CADH1AADH7KMT2A
Hydrochloric Acid SCHEMBL3741186 0.76 ADH1B (0.95) ADH1BADH1CADH1AADH7KMT2A
SCHEMBL23009349 0.75 ADH1B (0.47) ADH1BADH1CADH1AADH7KMT2A
SCHEMBL656733 0.74 ADH1B (0.56) ADH1BADH1CADH1AADH7KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106518757-A Method for synthesizing 2-halo-3-substited alkylsulfonyl pyridine and intermediate compound thereof through microwave method 山东师范大学 2017-03-22 CN claimed