Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827823 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2L3MBTL1GAAGFERPBRM1 | |
| SCHEMBL10676844 | 0.79 | L3MBTL1 (1.00) | SMN1; SMN2L3MBTL1GAAGFERALDH1A1 | |
| SCHEMBL17926939 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2L3MBTL1GAAGFERTP53 | |
| SCHEMBL27407052 | 0.77 | SMN1; SMN2 (0.62) | SMN1; SMN2L3MBTL1GAAGFERALDH1A1 | |
| SCHEMBL10673115 | 0.76 | SMN1; SMN2 (0.60) | SMN1; SMN2L3MBTL1GAAGFERALDH1A1 | |
| SCHEMBL10668061 | 0.75 | L3MBTL1 (0.72) | SMN1; SMN2L3MBTL1GAAGFERALDH1A1 | |
| SCHEMBL16796853 | 0.72 | L3MBTL1 (0.68) | SMN1; SMN2L3MBTL1GAAGFERALDH1A1 | |
| SCHEMBL29559516 | 0.72 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1GAAGFERALDH1A1 | |
| SCHEMBL10678134 | 0.72 | L3MBTL1 (0.76) | SMN1; SMN2L3MBTL1GAAGFERALDH1A1 | |
| SCHEMBL16797013 | 0.72 | L3MBTL1 (0.68) | SMN1; SMN2L3MBTL1GAAGFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104540800-B | Process for the preparation of (2Z,5Z)-5-(3-chloro-4- ((R)-2,3-dihydroxypropoxy)benzylidene)-2-(propylimino)-3-(o-tolyl)thiazolidin-4-one and intermediate used in said process | 埃科特莱茵药品有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-104540800-B | Process for the preparation of (2Z,5Z)-5-(3-chloro-4- ((R)-2,3-dihydroxypropoxy)benzylidene)-2-(propylimino)-3-(o-tolyl)thiazolidin-4-one and intermediate used in said process | 埃科特莱茵药品有限公司 | 2017-05-10 | — | — | CN | disclosed |