Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | KRAS | P01116 | 7/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418013 | 0.81 | KMT2A (0.60) | HTR2AHTR2CNTSR1HTR7KRAS | |
| SCHEMBL27872943 | 0.81 | KMT2A (0.41) | HTR2AHTR2CNTSR1PRMT5KMT2A | |
| SCHEMBL3478164 | 0.80 | HTR2A (0.63) | HTR2AHTR2CNTSR1HTR7KRAS | |
| SCHEMBL2008953 | 0.80 | HTR2A (0.55) | HTR2AHTR2CNTSR1HTR7KRAS | |
| SCHEMBL21810428 | 0.80 | NTSR1 (0.57) | HTR2AHTR2CNTSR1HTR7KRAS | |
| SCHEMBL28189356 | 0.79 | NTSR1 (0.53) | HTR2AHTR2CNTSR1KMT2A | |
| SCHEMBL27591506 | 0.79 | HTR2A (0.58) | HTR2AHTR2CKRASSLC6A2PRMT5 | |
| SCHEMBL11893595 | 0.79 | HTR2A (0.54) | HTR2AHTR2CNTSR1HTR7KRAS | |
| SCHEMBL4485443 | 0.77 | NTSR1 (0.52) | HTR2AHTR2CNTSR1HTR7KRAS | |
| SCHEMBL14061899 | 0.77 | HTR2A (0.59) | HTR2AHTR2CNTSR1HTR7KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103626742-B | Bi-aryl meta-pyrimidine inhibitors of kinases | 塔格根公司 | 2017-04-26 | — | — | CN | disclosed |