SCHEMBL28144159

SCHEMBL28144159

[CH2]c1occ2cc(C(F)(F)F)ccc12

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 9/20 0.36
BACE1 P56817 1/20 0.36
PIM1 P11309 1/20 0.36
PIM2 Q9P1W9 1/20 0.36
HSD17B10 Q99714 1/20 0.34
EPHX2 P34913 1/20 0.33
F7 P08709 1/20 0.33
F3 P13726 1/20 0.33
MAPT P10636 1/20 0.33
PARP1 P09874 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PKM P14618 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9998180 0.78 KIF11 (0.36) KIF11BACE1PIM1PIM2HSD17B10
SCHEMBL28149904 0.75 CYP1A2 (0.37) BACE1
SCHEMBL28149924 0.74 KIF11 (0.41) KIF11PIM1HSD17B10PKMKDM4E
SCHEMBL15881490 0.74 PIM1 (0.36) KIF11BACE1PIM1PIM2HSD17B10
SCHEMBL27334497 0.71 CYP2A6 (0.37) BACE1PIM1MAPTALDH1A1KDM4E
SCHEMBL28149963 0.71 CYP1A2 (0.42) KIF11BACE1HSD17B10MAPTALDH1A1
SCHEMBL10901779 0.70 KIF11 (0.49) KIF11PIM1EPHX2MAPTALDH1A1
SCHEMBL12320899 0.69 BACE1 (0.48) KIF11BACE1PIM1PIM2HSD17B10
SCHEMBL12310186 0.69 BACE1 (0.48) KIF11BACE1PIM1PIM2HSD17B10
SCHEMBL12473661 0.69 BACE1 (0.48) KIF11BACE1PIM1PIM2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106659161-B Amide compound and its harmful arthropod prevent and kill off purposes 住友化学株式会社 2019-08-02 CN disclosed
CN-106572659-B Harmful arthropod agent for preventing and eliminating containing amide compound 住友化学株式会社 2019-05-10 CN disclosed
CN-106659161-A Amide compound and use of same for noxious arthropod control 住友化学株式会社 2017-05-10 CN disclosed
CN-106572659-A Noxious arthropod control agent containing amide compound 住友化学株式会社 2017-04-19 CN disclosed