SCHEMBL28144591

SCHEMBL28144591

CCCCCCCCC1=Cc2cc(CCCCCCCC)cc3cccc(c23)C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.40
SLC6A4 P31645 3/20 0.40
HTR2A P28223 2/20 0.40
HTR2C P28335 2/20 0.40
DRD2 P14416 1/20 0.40
ALOX5 P09917 1/20 0.36
LPL P06858 3/20 0.36
LIPG Q9Y5X9 3/20 0.36
PTGS2 P35354 4/20 0.36
KCNH2 Q12809 1/20 0.36
CYP3A4 P08684 2/20 0.33
ESR1 P03372 2/20 0.33
ADRA2A P08913 2/20 0.33
ADORA3 P0DMS8 2/20 0.33
TACR2 P21452 2/20 0.33
SLC6A3 Q01959 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
SHBG P04278 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28299144 1.00 SLC6A2 (0.40) SLC6A2SLC6A4HTR2AHTR2CDRD2
SCHEMBL28412778 0.85 KCNH2 (0.40) SLC6A2SLC6A4HTR2AHTR2CDRD2
SCHEMBL28736811 0.84 CYP3A4 (0.39) SLC6A2SLC6A4HTR2AHTR2CDRD2
SCHEMBL28759275 0.79 CYP3A4 (0.40) HTR2AKCNH2CYP3A4KDM4EALDH1A1
SCHEMBL3433778 0.76 CYP3A4 (0.45) HTR2ACYP3A4KDM4EALDH1A1HSD17B10
SCHEMBL29922564 0.74 HTR2A (0.47) SLC6A2SLC6A4HTR2AHTR2CDRD2
SCHEMBL27083008 0.74 PTGS2 (0.48) SLC6A2SLC6A4HTR2AHTR2CLPL
SCHEMBL5613920 0.73 HTR2A (0.48) SLC6A2SLC6A4HTR2AHTR2CDRD2
SCHEMBL15993628 0.72 TDP1 (0.47) LPLLIPGPTGS2KCNH2CYP3A4
SCHEMBL29137337 0.69 CYP3A4 (0.48) HTR2AHTR2CDRD2CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105794009-B The light emitting device that frequency relies on 韦克森林大学 2019-02-19 CN disclosed
CN-104170113-B Electroluminescent devices and applications thereof 韦克森林大学 2017-05-17 CN disclosed