SCHEMBL28144752

SCHEMBL28144752

B.CCCCCONC(=O)CCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.53
TRPV1 Q8NER1 2/20 0.53
CNR1 P21554 1/20 0.50
CASP2 P42575 1/20 0.47
CTSD P07339 1/20 0.45
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
EPHX1 P07099 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HTR2C P28335 1/20 0.40
NAAA Q02083 1/20 0.39
DGKA P23743 1/20 0.39
FAAH O00519 1/20 0.39
EPHX2 P34913 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9281603 0.98 CNR2 (0.54) CNR2TRPV1CNR1CASP2CTSD
SCHEMBL27385830 0.96 CNR2 (0.57) CNR2TRPV1CNR1CASP2CTSD
SCHEMBL21415423 0.92 CNR2 (0.51) CNR2TRPV1CNR1CASP2CTSD
SCHEMBL3758968 0.88 CNR2 (0.66) CNR2TRPV1CNR1HDAC3HDAC1
SCHEMBL8313083 0.86 TRPV1 (0.63) CNR2TRPV1CNR1HSP90AA1DGKA
SCHEMBL5187690 0.83 CNR2 (0.56) CNR2TRPV1CNR1CTSDHDAC3
SCHEMBL840650 0.83 CTSD (0.52) CNR2TRPV1CNR1CASP2CTSD
SCHEMBL13225167 0.82 CNR2 (0.44) CNR2TRPV1CNR1CASP2CTSD
SCHEMBL4141685 0.82 CNR2 (0.50) CNR2TRPV1CNR1EPHX1HSP90AA1
SCHEMBL28945729 0.82 CNR2 (0.50) CNR2TRPV1CNR1EPHX1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104072394-B The manufacture method of nitrile compound 住友化学株式会社 2017-04-05 CN disclosed
CN-104072528-A Preparation method for boron compound SUMITOMO CHEMICAL CO 2014-10-01 CN disclosed
CN-104072394-A Method for producing a nitrile compound SUMITOMO CHEMICAL CO 2014-10-01 CN disclosed