Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756834 | 0.97 | TSHR (0.35) | TSHRMAPK1CA12CA1CA2 | |
| Hydrogen Sulfide SCHEMBL28249500 | 0.95 | TSHR (0.34) | TSHRMAPK1CA12CA1CA2 | |
| SCHEMBL8978078 | 0.78 | CA12 (0.32) | TSHRMAPK1CA12CA1CA2 | |
| SCHEMBL9780354 | 0.77 | — | — | |
| SCHEMBL19687777 | 0.75 | — | — | |
| SCHEMBL1325482 | 0.73 | CA12 (0.31) | CA12CA1CA2CA9 | |
| SCHEMBL3692254 | 0.73 | — | — | |
| SCHEMBL253162 | 0.73 | — | — | |
| SCHEMBL4793302 | 0.73 | — | — | |
| SCHEMBL974911 | 0.73 | TSHR (0.36) | TSHRMAPK1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106659700-A | Sulfur fluoride (VI) compound and preparation method thereof | 斯克里普斯研究所 | 2017-05-10 | — | — | CN | disclosed |