3-Hydroxycoumarin

3-Hydroxycoumarin

SCHEMBL28145356

C#N.O=c1oc2ccccc2cc1O

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.89
TYR P14679 1/20 0.89
DAO P14920 1/20 0.89
AKR1B1 P15121 1/20 0.89
LMNA P02545 3/20 0.57
SMN1; SMN2 Q16637 3/20 0.55
POLB P06746 1/20 0.55
MAOB P27338 4/20 0.54
CA12 O43570 3/20 0.54
CA9 Q16790 3/20 0.54
CA1 P00915 2/20 0.54
CA3 P07451 1/20 0.54
TSHR P16473 1/20 0.54
CA4 P22748 1/20 0.54
CA6 P23280 1/20 0.54
CA5A P35218 1/20 0.54
CA7 P43166 1/20 0.54
GPR35 Q9HC97 1/20 0.54
CA14 Q9ULX7 1/20 0.54
CA5B Q9Y2D0 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Hydroxycoumarin SCHEMBL76090 0.94 HPGD (1.00) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL29397603 0.94 HPGD (1.00) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL28258929 0.92 HPGD (0.96) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL31476361 0.89 HPGD (0.89) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL16011243 0.87 HPGD (0.86) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL3837239 0.87 HPGD (0.86) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL28805372 0.87 HPGD (0.86) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL27836527 0.87 HPGD (0.86) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL28186257 0.87 HPGD (0.86) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL6401867 0.86 HPGD (0.83) HPGDTYRDAOAKR1B1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108064315-A Method for detecting influenza 西菲伊德公司 2018-05-22 CN disclosed
CN-106661611-A Method for detecting Trichomonas vaginalis 西菲伊德公司 2017-05-10 CN disclosed