3-Hydroxycoumarin

3-Hydroxycoumarin

SCHEMBL76090

O=c1oc2ccccc2cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 1.00
TYR P14679 1/20 1.00
DAO P14920 1/20 1.00
AKR1B1 P15121 1/20 1.00
LMNA P02545 3/20 0.62
SMN1; SMN2 Q16637 3/20 0.60
POLB P06746 1/20 0.60
MAOB P27338 4/20 0.59
CA12 O43570 3/20 0.59
CA9 Q16790 3/20 0.59
CA1 P00915 2/20 0.59
CA3 P07451 1/20 0.59
TSHR P16473 1/20 0.59
CA4 P22748 1/20 0.59
CA6 P23280 1/20 0.59
CA5A P35218 1/20 0.59
CA7 P43166 1/20 0.59
GPR35 Q9HC97 1/20 0.59
CA14 Q9ULX7 1/20 0.59
CA5B Q9Y2D0 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Hydroxycoumarin SCHEMBL29397603 1.00 HPGD (1.00) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL28258929 0.98 HPGD (0.96) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL28145356 0.94 HPGD (0.89) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL31476361 0.94 HPGD (0.89) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL16011243 0.93 HPGD (0.86) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL28805372 0.93 HPGD (0.86) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL3837239 0.93 HPGD (0.86) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL28186257 0.93 HPGD (0.86) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL27836527 0.93 HPGD (0.86) HPGDTYRDAOAKR1B1LMNA
3-Hydroxycoumarin SCHEMBL6401867 0.91 HPGD (0.83) HPGDTYRDAOAKR1B1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13369 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107279-A1 METHOD FOR ASSESSING VIABILITY OF MICROBIAL STRAINS Kanvas Biosciences, Inc. (US) 2026-05-21 WO claimed
WO-2026102006-A1 METHOD FOR IDENTIFYING MICROBIAL STRAINS Kanvas Biosciences, Inc. (US) 2026-05-15 WO claimed
WO-2026102332-A1 NERVE AND TUMOR HOMING AGENTS AND METHODS OF USE THEREOF Blaze Bioscience, Inc. (US) 2026-05-15 WO claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
EP-4676949-A2 ANTIGEN BINDING MOLECULES AND METHODS OF USE Kite Pharma, Inc. (US) 2026-01-14 EP claimed
US-20260010026-A1 ENGINEERED LIQUID CRYSTAL SHUTTER AS A DYNAMIC LONG-PASS OPTICAL FILTER BLAZE BIOSCIENCE INC (US) 2026-01-08 US claimed
EP-4661841-A1 DEGARELIX ORGANIC SOLVENT FORMULATIONS Tolmar International Limited (IE) 2025-12-17 EP claimed
EP-4642492-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-4634235-A1 CD70 ANTI-IDIOTYPE ANTIBODIES Allogene Therapeutics, Inc. (US) 2025-10-22 EP claimed
US-4620850-A HYDROXYBENZOLFURANONE WELLA AKTIENGESELLSCHAFT (DE) 1986-11-04 US claimed
US-4616033-A 7 hydroxy-coumarin as a treatment for high protein oedemas LAMORNA INVESTMENTS PROPRIETARY LTD. (AU) 1986-10-07 US claimed
EP-0172893-A1 TREATMENT OF HIGH PROTEIN OEDEMAS IN ANIMALS LAMORNA INVESTMENTS PROPRIETARY LIMITED (AU) 1986-03-05 EP claimed
WO-1985003864-A1 TREATMENT OF HIGH PROTEIN OEDEMAS BY DIRECT APPLICATION OF BENZO-PYRONES CASLEY SMITH JOHN ROYLE (AU) 1985-09-12 WO claimed
WO-1985003865-A1 TREATMENT OF HIGH PROTEIN OEDEMAS IN ANIMALS CASLEY SMITH JOHN ROYLE 1985-09-12 WO claimed
EP-0111746-A2 Sulfonic-acid esters of hydroxycoumarines, their preparation and medicines containing them BASF Aktiengesellschaft (DE) 1984-06-27 EP claimed
EP-0026473-B1 OXIDATIVE HAIR-DYEING COMPOSITION Wella Aktiengesellschaft (DE) 1983-05-25 EP claimed
US-4308348-A SALMONELLA, SERRATIA, PROTEUS, PROVIDENCIA LABORATOIRE DE RECHERCHE API (FR) 1981-12-29 US claimed
EP-0026473-A1 Oxidative hair-dyeing composition Wella Aktiengesellschaft (DE) 1981-04-08 EP claimed
WO-1981000810-A1 COMPOSITION ALLOWING THE COLORATION OF HAIR BY OXIDATION WELLA AG (DE) 1981-04-02 WO claimed