Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28129050 | 0.93 | TLR8 (0.43) | TLR8HPGDMAPK1MEN1KMT2A | |
| SCHEMBL18297270 | 0.82 | TLR8 (0.47) | TLR8HPGDMAPK1MEN1KMT2A | |
| SCHEMBL28265084 | 0.79 | TLR8 (0.52) | TLR8MEN1KMT2ATLR7NPC1 | |
| SCHEMBL28145411 | 0.78 | HPGD (0.45) | TLR8HPGDMAPK1MEN1KMT2A | |
| SCHEMBL28810372 | 0.77 | TLR8 (0.45) | TLR8HPGDMAPK1MEN1KMT2A | |
| SCHEMBL28840490 | 0.76 | TLR8 (0.45) | TLR8HPGDMAPK1MEN1KMT2A | |
| SCHEMBL3021829 | 0.75 | TLR8 (0.56) | TLR8HPGDMAPK1MEN1KMT2A | |
| SCHEMBL18297269 | 0.73 | TLR8 (0.49) | TLR8HPGDMAPK1MEN1KMT2A | |
| Formamide SCHEMBL19951508 | 0.71 | TLR8 (0.48) | TLR8HPGDMAPK1MEN1KMT2A | |
| SCHEMBL10325045 | 0.71 | TLR8 (0.45) | TLR8HPGDMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749023-A | As the substituted benzazepine of toll-like receptor conditioning agent | 帆德制药股份有限公司 | 2017-05-31 | — | — | CN | disclosed |