SCHEMBL28146286

SCHEMBL28146286

C1CCC(NC2CCCCC2)CC1.C[C](C)C

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.75
HSD17B10 Q99714 1/20 0.75
SIGMAR1 Q99720 2/20 0.44
THRB P10828 1/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
EPHX1 P07099 7/20 0.43
EPHX2 P34913 3/20 0.43
CYP3A4 P08684 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
ADH1B P00325 2/20 0.43
ADH1C P00326 2/20 0.43
ADH1A P07327 2/20 0.43
KDM4E B2RXH2 2/20 0.43
ADH4 P08319 1/20 0.43
TP53 P04637 1/20 0.43
MAPT P10636 1/20 0.43
ADH7 P40394 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL20551274 0.88 ALDH1A1 (0.67) ALDH1A1HSD17B10THRBATML3MBTL1
Ethane SCHEMBL9776531 0.87 ALDH1A1 (0.86) ALDH1A1HSD17B10SIGMAR1THRBATM
SCHEMBL20733078 0.87 ALDH1A1 (1.00) ALDH1A1HSD17B10SIGMAR1THRBATM
SCHEMBL21375316 0.87 ALDH1A1 (1.00) ALDH1A1HSD17B10SIGMAR1THRBATM
SCHEMBL18657085 0.87 ALDH1A1 (1.00) ALDH1A1HSD17B10SIGMAR1THRBATM
SCHEMBL24771540 0.87 ALDH1A1 (1.00) ALDH1A1HSD17B10SIGMAR1THRBATM
SCHEMBL24771539 0.87 ALDH1A1 (1.00) ALDH1A1HSD17B10SIGMAR1THRBATM
SCHEMBL25122871 0.87 ALDH1A1 (1.00) ALDH1A1HSD17B10SIGMAR1THRBATM
SCHEMBL24839013 0.87 ALDH1A1 (1.00) ALDH1A1HSD17B10SIGMAR1THRBATM
SCHEMBL18657086 0.87 ALDH1A1 (1.00) ALDH1A1HSD17B10SIGMAR1THRBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106700120-A Amine catalysts for polyurethane foams 霍尼韦尔国际公司 2017-05-24 CN disclosed