Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.51 |
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29915690 | 0.98 | HTR2C (0.66) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| Hydrochloric Acid SCHEMBL4893521 | 0.98 | HTR2C (0.66) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL17224421 | 0.88 | HTR2C (0.63) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| Hydrochloric Acid SCHEMBL17222851 | 0.87 | HTR2C (0.64) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| Hydrochloric Acid SCHEMBL4892516 | 0.83 | HTR2C (0.64) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL14321224 | 0.83 | HTR2C (0.61) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL5541872 | 0.83 | HTR2C (0.61) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL20757472 | 0.82 | CHRNB2 (0.62) | HTR2CNOTUMCHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL4890490 | 0.82 | HTR2C (0.62) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL15317739 | 0.81 | HTR2C (0.58) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106794364-A | Substituted 4-phenylpiperidines, their preparation and use | 哥伦比亚大学董事会 | 2017-05-31 | — | — | CN | disclosed |