SCHEMBL28147443

SCHEMBL28147443

Fc1ccc(-c2nc(-c3ccccc3)c3ccccc3n2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.71
KMT2A Q03164 3/20 0.71
ATM Q13315 1/20 0.71
ADORA2A P29274 2/20 0.66
ABCG2 Q9UNQ0 3/20 0.62
SCN9A Q15858 4/20 0.56
MAPT P10636 3/20 0.56
LMNA P02545 1/20 0.56
DPP4 P27487 1/20 0.55
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 1/20 0.55
PPARG P37231 1/20 0.55
NCOA2 Q15596 1/20 0.55
NCOA1 Q15788 1/20 0.55
NCOA3 Q9Y6Q9 1/20 0.55
PDE5A O76074 1/20 0.53
NUDT1 P36639 1/20 0.51
KDM1A O60341 1/20 0.51
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28147464 1.00 MEN1 (0.71) MEN1KMT2AATMADORA2AABCG2
SCHEMBL31300371 0.98 MEN1 (0.69) MEN1KMT2AATMADORA2AABCG2
SCHEMBL16436798 0.89 MEN1 (0.86) MEN1KMT2AATMADORA2AABCG2
SCHEMBL22483256 0.89 MEN1 (0.80) MEN1KMT2AATMADORA2AABCG2
SCHEMBL22058673 0.89 MEN1 (0.80) MEN1KMT2AATMADORA2AABCG2
SCHEMBL23606297 0.89 MEN1 (0.86) MEN1KMT2AATMADORA2AABCG2
SCHEMBL30484133 0.89 MEN1 (0.79) MEN1KMT2AATMADORA2AABCG2
SCHEMBL4393626 0.89 MEN1 (0.79) MEN1KMT2AATMADORA2AABCG2
Ammonia Solution, Strong SCHEMBL29210690 0.87 MEN1 (0.77) MEN1KMT2AATMADORA2AABCG2
SCHEMBL29416679 0.83 ADORA2A (0.66) MEN1KMT2AATMADORA2AABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112979548-B Compound and application thereof 北京鼎材科技有限公司 2025-06-24 CN disclosed
CN-113651823-B Compound and application thereof 北京鼎材科技有限公司 2025-06-13 CN disclosed
CN-112778281-B Compound and application thereof 北京鼎材科技有限公司 2025-04-04 CN disclosed
CN-113666913-B Organic compound and application thereof in organic light-emitting field 北京鼎材科技有限公司 2024-09-06 CN disclosed
CN-112430230-B Organic compound and organic electroluminescent device containing the same 北京鼎材科技有限公司 2024-02-09 CN disclosed
CN-113666913-A Organic compound and application thereof in organic light-emitting field 北京鼎材科技有限公司 2021-11-19 CN disclosed
CN-113651823-A Compound and application thereof 北京鼎材科技有限公司 2021-11-16 CN disclosed
CN-113512028-A Compound and application thereof 北京鼎材科技有限公司 2021-10-19 CN disclosed
CN-112979548-A Compound and application thereof 北京鼎材科技有限公司 2021-06-18 CN disclosed
CN-112979535-A Compound and application thereof 北京鼎材科技有限公司 2021-06-18 CN disclosed
CN-112778281-A Compound and application thereof 北京鼎材科技有限公司 2021-05-11 CN disclosed
CN-112430230-A Organic compound and organic electroluminescent device containing the same 北京鼎材科技有限公司 2021-03-02 CN disclosed
CN-106632086-B 2- (2- iodo aryl) quinazoline compounds and preparation method thereof 江西省林业科学院 2019-08-09 CN disclosed
CN-106632086-A 2-(2-iodoaryl)quinazoline compound and preparation method thereof 江西省林业科学院 2017-05-10 CN disclosed