Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249802 | 0.96 | BCHE (0.54) | BCHEFAAHTLR2MMEACE | |
| SCHEMBL3143813 | 0.96 | BCHE (0.54) | BCHEFAAHTLR2MMEACE | |
| SCHEMBL249801 | 0.96 | BCHE (0.54) | BCHEFAAHTLR2MMEACE | |
| SCHEMBL30918986 | 0.94 | FAAH (0.55) | BCHEFAAHTLR2MMEACE | |
| SCHEMBL17626995 | 0.94 | FAAH (0.55) | BCHEFAAHTLR2MMEACE | |
| SCHEMBL6702717 | 0.94 | FAAH (0.55) | BCHEFAAHTLR2MMEACE | |
| SCHEMBL3953856 | 0.94 | FAAH (0.55) | BCHEFAAHTLR2MMEACE | |
| SCHEMBL21585496 | 0.94 | FAAH (0.55) | BCHEFAAHTLR2MMEACE | |
| SCHEMBL6702715 | 0.94 | FAAH (0.55) | BCHEFAAHTLR2MMEACE | |
| SCHEMBL28403707 | 0.94 | FAAH (0.55) | BCHEFAAHTLR2MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368133-A | Urea peptidomimetic boronic acid compounds and its pharmaceutical composition, preparation method and purposes | 北京大学 | 2018-08-03 | — | — | CN | claimed |
| CN-106588965-A | Urea peptidomimetic boric acid compound as well as pharmaceutical composition, preparation method and application thereof | 北京大学 | 2017-04-26 | — | — | CN | claimed |
| CN-108368133-A | Urea peptidomimetic boronic acid compounds and its pharmaceutical composition, preparation method and purposes | 北京大学 | 2018-08-03 | — | — | CN | disclosed |
| CN-106588965-A | Urea peptidomimetic boric acid compound as well as pharmaceutical composition, preparation method and application thereof | 北京大学 | 2017-04-26 | — | — | CN | disclosed |